What we mean when we say a drug "works"
Psychedelic trials report dramatic numbers. Understanding what those numbers measure — and what they quietly leave out — is the first step to reading them honestly.
Essays
Pieces that take their time — about what the science shows, what it doesn’t, and what it asks of us.
Psychedelic trials report dramatic numbers. Understanding what those numbers measure — and what they quietly leave out — is the first step to reading them honestly.
"Set and setting" is often treated as a slogan. In clinical practice it is closer to the active ingredient — and treating it casually is where harm tends to begin.
The dramatic part is over in a day. Whether anything changes depends on the unglamorous weeks that follow — and on having somewhere to bring what surfaced.
The clinical label describes what medicines have failed to do, not what a person is. That distinction changes how we read the research — and how we treat the people in it.
Trauma is not only a memory problem. Understanding why it lives in the body helps explain why some emerging therapies work on the body's terms, not the mind's alone.
If psychedelic therapy becomes a real treatment, the next question is not whether it works but who will be able to reach it — and whether access will follow need or money.