The lead essay

What we mean when we say a drug "works"

Psychedelic trials report dramatic numbers. Understanding what those numbers measure — and what they quietly leave out — is the first step to reading them honestly.

Research & science

Higher Place editors · 9 min read

Read the essay
What we mean when we say a drug "works"

Latest essays

Thinking, not takes

The room matters as much as the molecule
EssayPsychedelic therapy

"Set and setting" is often treated as a slogan. In clinical practice it is closer to the active ingredient — and treating it casually is where harm tends to begin.

Higher Place editors · 6 May 2026 · 8 min read

After the session: why integration is the real work
EssayPsychedelic therapy

The dramatic part is over in a day. Whether anything changes depends on the unglamorous weeks that follow — and on having somewhere to bring what surfaced.

Higher Place editors · 28 April 2026 · 7 min read

"Treatment-resistant" doesn't mean person-resistant
EssayDepression & anxiety

The clinical label describes what medicines have failed to do, not what a person is. That distinction changes how we read the research — and how we treat the people in it.

Higher Place editors · 19 April 2026 · 6 min read

The body keeps the appointment
EssayTrauma & PTSD

Trauma is not only a memory problem. Understanding why it lives in the body helps explain why some emerging therapies work on the body's terms, not the mind's alone.

Higher Place editors · 10 April 2026 · 8 min read

Who gets to be a patient?
EssayPolicy & access

If psychedelic therapy becomes a real treatment, the next question is not whether it works but who will be able to reach it — and whether access will follow need or money.

Higher Place editors · 2 April 2026 · 7 min read

Practical guides

Start here

How to talk to your doctor about psychedelic therapy
GuideMental health

A calm, practical guide to raising the subject with a clinician — what to ask, what to expect, and how to tell credible care from a sales pitch.

Higher Place editors · 9 May 2026 · 7 min read

How to think about set and setting
GuidePsychedelic therapy

The two oldest words in this field, explained without mysticism — what they actually refer to, why clinicians take them so seriously, and how to apply the idea.

Higher Place editors · 22 April 2026 · 5 min read

How to support someone after a difficult experience
GuideHarm reduction

A harm-reduction guide for friends and family — how to be useful to someone shaken by a psychedelic experience, and how to recognise when to seek help.

Higher Place editors · 30 March 2026 · 6 min read

The newsletter

One careful letter, every other week

New essays and guides, plus a short, honest note on what the evidence does and doesn’t yet show.

A considered email every other week. No noise, unsubscribe anytime.